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Biogenic Synthesized Ag/Au Nanoparticles: Production, Characterization, and Applications

[ Vol. 14 , Issue. 2 ]


Nelson Duran * and Amedea B. Seabra   Pages 82 - 94 ( 13 )


Background: Bimetallic silver-gold nanoparticles (Ag/Au NPs) with different structures have recently gained scientific attention due to their new and superior properties in comparison with metallic NPs made from a single metal. Ag/Au NPs (alloy or core-shell structures) have been applied to several biomedical, technological, and environmental applications. The potential applications of Ag/Au NPs are widespread yet poorly investigated in comparison with monometallic NPs. Besides traditional chemical and physical routes to synthesize bimetallic Ag/Au NPs, biogenic protocols are considered cost-effective, simple, and environmentally friendly. Despite their simplicity, biogenic routes to synthesize Ag/Au NPs are less explored than traditional synthetic protocols.

Methods: In this context, we present a review and discuss recent progress in the preparation of bimetallic Ag/Au NPs with different morphologies, structures, and size distributions using biogenic synthetic protocols.

Results: Biogenic synthesis using plant extracts, algae, bacteria, fungi, and other biological agents are presented and discussed. The characterization and potential applications of biogenically synthesized Ag/Au NPs in the different areas of medicine and biological applications, such as antibacterial, anticandidal, anticancer, antidiabetes, and as sensors for clinical diagnosis are presented and discussed.

Conclusion: Finally, challenges and drawbacks in the biological routes for the preparation of Ag/Au NPs for industrial applications are also discussed.


Biogenic synthesis, Ag/Au nanoparticles, Bimetallic nanoparticles, Green chemistry, Bionanotechnolgy, Noble nanoparticles.


Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP, Center for Natural and Human Sciences, Federal University of ABC, Santo Andre, SP

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