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Nanocrystals: A Strategic Approach for the Development of Futuristic Nano-formulations and their Patenting Applicability

Author(s):

Surya Goel*, Vijay Agarwal and Monika Sachdeva   Pages 1 - 13 ( 13 )

Abstract:


Background: Nanocrystals have been found as potent, beneficial, and advantageous nanocarrier systems for ameliorating the solubility, bioavailability and permeability of those drug candidates that are less water-soluble and permeable. Such an approach possesses many complications that require more research work.

Objective: The main objective of the manuscript is to prepare a review on all the aspects of nanocrystals that includes their advantages, recent advancements, preparation methods, recent patents, marketed products, and some patents related to their characterization techniques.

Methods: This manuscript has been accrued through the help of online and offline journals, books, and other accessible sources. This field involves new developments or inventions in the novel nanocarrier system.

Results: Nanocrystals have been found to exhibit better potentiality to sort out different problems like poor drug absorption, drug-associated side effects, targeted drug delivery. In the last decade, these nanocarriers have been opted for resolving the problem produced due to less soluble drugs. By conducting more research, this field can be more beneficial to the health sector.

Conclusion: Nanocrystals contribute significantly to deliver several drugs via different routes like topical, oral ophthalmic, pulmonary and parenteral. This manuscript substantially shows the applicability and importance of nanocrystals as a drug delivery carrier to treat various health issues.

Keywords:

Nanocrystals, solubility, drug moieties, bioavailability, nanocrystal approach, patents.

Affiliation:

Dr. APJ Abdul Kalam Technical University, Vistar Yojna, Naya Khera, Jankipuram, Lucknow, Uttar Pradesh, Raj Kumar Goel Institute of Technology (Pharmacy), 5-Km. Stone, Delhi-Meerut Road, Ghaziabad, Uttar Pradesh, ABESIT College of Pharmacy, 19 Km. Stone, National Highway-24, Vijay Nagar, Ghaziabad, Uttar Pradesh



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