Anupama Thapliyal, Roop Krishen Khar and Amrish Chandra* Pages 239 - 251 ( 13 )
Background: In this study, computational Artificial Neural Network (ANN) model is applied for optimisation and evaluation of silver nanoparticles (AgNPs) size in the bionanocomposite matrix. The primary purpose of this study is used a feed-forward ANN model to create a connection between the output as the size of Ag–NPs, with four inputs variables, including AgNO3 concentration, the weight percentage of starch, Bentonite amount and Gallic acid concentration.
Method: Silver nanoparticles were synthesised via biogenic green reduction method. The fast Levenberg– Marquardt (LM) backpropagation algorithm applied for the training of ANN model in this research. The optimised ANN is a multilayer perceptron (MLP) which is a kind of feed forward (4- 10-1) network has an input layer with 4 nodes, hidden layers with 10 neurones, and an output layer with 1 node found a fitness function.
Results: The output results of developed computational ANN model were compared to its predictive values of the size of silver nanoparticles regarding two statistical parameters, the coefficient of determination (R2) and mean square error (MSE) of data set. It observed that ANN predicted values are close to the actual values and well fitted to the data. The mean square error(MSE) is 0.03, and a regression is about 1.
Conclusion: AgNO3 concentration has the most likely factor affecting the size of silver nanoparticles (Ag–NPs) and this makes possible to develop a green reduction method for the preparation of silver nanoparticles. This study confirms that employing ANN method with LM feed forward (4-10-1) network is a useful tool with cost-effective for predicting the results of analysis and modelling of the chemical reactions.
Artificial neural network, silver nanoparticles, green-reduction method, bio-nanocomposite, modelling, LM algorithm.
Amity Institute of Pharmacy, Amity University, Noida, B.S. Anangpuria Institute of Pharmacy, Haryana, Amity Institute of Pharmacy, Amity University, Noida