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Optical Biochemical Sensor Using Photonic Crystal Nano-ring Resonators for the Detection of Protein Concentration

[ Vol. 13 , Issue. 4 ]

Author(s):

Ahmad Mohebzadeh Bahabady, Saeed Olyaee* and Hassan Arman   Pages 421 - 425 ( 5 )

Abstract:


Background: One of the important molecules in the human body is protein. The proteins are incredibly complex chains of smaller molecules namely amino acids. After the invention of biosensor, optical sensing mechanisms received considerable attention in the applications of the chemical and biochemical sensors in various applications such as industrial process control. Photonic crystals (PhCs) are as an attractive sensing platforms due to the control light in very small dimensions. The photonic crystals can control and guide the photons in the periodic lattice. In this paper, an optical biochemical sensor is presented based on photonic crystal nano-ring resonators for detection of protein concentration.

Methods: In biochemical sensors, the effective refractive index of sensing hole can be changed by binding the biomolecule to the sensing hole. The resonant wavelength of the transmission spectrum or intensity of the transmission spectrum can be shifted resulting from refractive index variations. The proposed biochemical sensor constructed by photonic crystal nano-ring resonator using twodimensional PhC is designed and simulated. In our design, the hexagonal lattice of air holes in the dielectric slab is used.

Results: Two-dimensional finite-difference time-domain (2-D FDTD) method is used for simulating the propagation of electromagnetism wave and plane-wave expansion (PWE) approach is applied to analyze the proposed sensor. Biochemical sensor is presented for identifying small changes in the refractive index. The detection of protein concentration from 0% to 35% as one of its applications has been presented. The biochemical sensor structure includes a ring resonator shaped by consecutive curves and two waveguides. By binding protein concentration into the sensing hole, the refractive index of sensing hole is changed and the intensity of the transmission spectrum is shifted to the lower values. The results reveal that the quality factor and the sensitivity of proposed biochemical sensor are respectively obtained about 2960 and 925.02 a.u./RIU.

Conclusion: The biochemical sensor structure includes a ring resonator and two waveguides. The ring resonator is shaped by consecutive curves. By binding protein concentration into the sensing hole, the refractive index of sensing hole is changed and the intensity of the transmission spectrum is shifted to lower values. By increasing the protein concentration of the sensing hole, the intensity of the transmission spectrum is shifted to lower values. The normalized curve of the intensity of the transmission spectrum shows approximately linear relationship between the protein concentration and intensity shift.

Keywords:

Biochemical, intensity, nano ring resonator, photonic crystal, protein concentration

Affiliation:

Nano-photonics and Optoelectronics Research Laboratory (NORLab), Faculty of Electrical Engineering, Shahid Rajaee Teacher Training University (SRTTU), Lavizan, 16788-15811, Tehran, Nano-photonics and Optoelectronics Research Laboratory (NORLab), Faculty of Electrical Engineering, Shahid Rajaee Teacher Training University (SRTTU), Lavizan, 16788- 15811, Tehran, Nano-photonics and Optoelectronics Research Laboratory (NORLab), Faculty of Electrical Engineering, Shahid Rajaee Teacher Training University (SRTTU), Lavizan, 16788-15811, Tehran

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